Articles

Commentaries
(1)Obesity-induced inflammatory changes in adipose tissue

(2)A radical explanation for glucose-induced ß-cell dysfunction

(3)It takes two to tango:mast cell and Schwann cell interactions in neurofibromas

(4)Tumbling down a different pathway to genetic instability

Commentaries
(1)Do allelic variants of SLC6A14 predispose to obesity?

(2)Genes required for B cell development

(3)Complement system on the attack in autoimmunity

(4)Dominent-negative diabetes insipidus and other endocrinopathies

Commentaries
(1)Hematopoietic stem cell gene therapy:selecting only the best

(2)Therapeutic CD154 antibody for lupus:promise for the future?

(3)LRP:a bright beacon at the blood-brain barrier

Commentaries
(1)Decreased elastin in vessel walls puts the pressure on

(2)The origin of FOXP3-expressing CD4+ regulatory T cells:thymus or periphery

(3)Tales from the crypt

(4)The TRAIL to arthritis

Commentaries
(1)What brings pericytes to tumor vessels?

(2)Receptor "cross talk"in innate immunity

(3)A novel role for uroguanylin in the regulation of sodium balance

Commentaries
(1)Hepatoprotection via the IL-6/stat3 pathway

(2)Selectin and selectin ligand binding:a bittersweet attraction

(3)Finding NEMO;genetic disorders of NF-kB activation

(4)Diabetes,microvascular complications , and cardiovascular complications:what is it about glucose?

Commentaries
(1)Turnover of lymphocytes and conceptual paradigms in HIV infection

(2)HATs off to Hop: recruitment of a class I histone deacetylase incriminates a novel transcriptional pathway that opposes cardiac hypertrophy

(3)Tracking autoimmune T cells in diabetes

(4)15-deoxy- 12,14-PGJ2: endogenous PPAR  ligand or minor eicosanoid degradation product?

Commentaries
(1)Evidence for a bone-kidney axis regulating phosphate homeostasis

(2)Come forth CD1d:HSP110 in the regulation of intestinal epithelial CD1d expression

(3)Dendritic cells and intestinal bacterial flora:a role for localized mucosal immune responses

(4)Cardica treponin T and familial hypertrophic cardiomyopathy:an energetic affair

(5)Hypertension:ß testing

(6)The host response to anthrax lethal toxin:unexpected observations

Commentaries
(1)Beta-Agonists and asthma:too much of a good thing?

(2)Thyroid hormone action:a binding contract

(3)Decrypting the role of Cripto in tumorigenesis

Perspective
(1)Targeted genetic repair:an emerging approach to genetic therapy

(2)Ribozyme-mediated revision of RNA and DNA

Commentary
(1)Ubiquitinated deiodinase:not dead yet

(2)Osteopontin:a bridge between the bone and the immune system

(3)Salicylic acid:an old dog,new tricks, and staphylococcal disease

Perspective
(1)Principles and practice of functional MRI of the human brain

(2)insights and treatment options for psychiatric disorders guided by functional MRI

Commentaries
(1)AIP1:a new player in TNF signaling

(2)Arginase:marker,effector,or candidate gene for asthma?

(3)An eye on insulin

(4)Tolerence:Of mice and men

Commentaries
(1)CT Screening:a trade-off of risks,benefits, and costs

(2)Molecular genetic-imaging:current and future perspectives

(3)Cardivascular nuclear magnetic resonance:basic and clinical applications

Commentaries
(1)Pulmonary Surfactant:A Front Line of Lung Host Defense

(2)The Mitochondriotoxic Domain of Vpr Determines HIV-1 Virulence

(3)A Matter of Life and Death:Cardiac Myocyte Apoptosis and Regeneration

Commentaries
(1)A friend within the heart:natiuretic peptide receptor signaling

(2)Double target for tumor mass destruction

(3)Peptide-based treatment for autoimmune diseases:learning how to handle a double-edged sword

(4)Tissue glycogen content and glucose intolerance

(5)Connecting the dots from Toll-like receptors to innate immune cells and inflammatory bowel disease

Commentaries
(1)Salt-sensitive hypertension:if only in were simple as rocket science

(2)Coordinated tumor immunity

(3)The fractalkine receptor CX3CRI is a key mediator of atherogenesis

(4)RANK ligand and the regulation of the skeletal remodeling

(5)Azathioprine:old drug,new actions

Commentaries
(1)The hunting of the snark:the elusive calcium receptor(s)

(2)Negative regulators of sodium transport in the kidney:Key factors in understanding salt-sensitive hypertension?

(3)Peanut allergy:a growing phenomenon

(4)Heparan sulfate:Antithrombitic or not?

(5)Transpalcental thyroxine and fetal development

Commentaries
(1)Integrating the quality of the cytotoxic response and tumor susceptibility into the design of protective vaccines in tumor immunotherapy

(2)Calcium and the heart: a question of life and death

(3)Solubel VEGF receptor Fltl:the elusive preeclampsia factor discovered?

(4)Nephrolithiasis:site of the initial solid phase?

Commentaries
(1)Oxidative stress and diabetic neuropathy:a new understanding of an old problem

(2)Insulins' effect on glucose production:direct or indirect?

(3)Insights into channel function via channel dysfunction

(4)The role of uncoupling protein 3 in human physiology

(4)RGS2: a "turn-off" in hypertension

Commentaries
(1)DAP12 signaling:from immune cells to bone modeling and brain myelination

(2)Artemis:guarding the small children and,now,the genome

(3)HIV protease inhibitors and atherosclerosis

(4)Endothelial lipase:direct evidence for a role in HDL metabolism

Perspective
(1)Rare genetic mutations shed light on the pathogenesis of Parkinson Disease

(2)Programmed cell death in amyotrophic lateral sclerosis

(3)Oxidative stress and nitration in neurodegeneration:Cause,effect,or association?

Perspective
(1)Series introduction:Neurodegeneration:What is it and where are we?

(2)Alzheimer disease therapy:Can the amyloid cascade be halted?