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Articles

JCI Editorials/Perspectives/Commentaries 2007

ISSUE EDITORIALS/PERSPECTIVES/COMMENTARIES
January 2007
Physician-scientist, heal thyself . . .
Andrew R. Marks
Abstract | Full text
February 2007
Hello, goodbye
Andrew R. Marks
Abstract | Full text


March 2007
Gene modifiers in cystic fibrosis
Frank J. Accurso , Marci K. Sontag
Abstract | Full text | PDF (Page 839)
Hepatic glucose sensing: does flux matter?
Masakazu Shiota, Mark A. Magnuson
Abstract | Full text | PDF (Page 841)
Growth hormone resurrects adult human thymus during HIV-1 infection
Kiki Tesselaar, Frank Miedema
Abstract | Full text | PDF (Page 844)
Discovering early molecular determinants of leukemogenesis
Grover C. Bagby
Abstract | Full text | PDF (Page 847)
Currying favor for the heart
Jonathan A. Epstein
Abstract | Full text


April 2007
Putting pancreatic cell plasticity to the test
Jorge Ferrer, Mercè Martín, Joan Marc Servitja
Abstract | Full text | PDF (Page 859)
HIF-1 and HIF-2: working alone or together in hypoxia?
Peter J. Ratcliffe
Abstract | Full text | PDF (Page 862)
HOX deregulation in acute myeloid leukemia
Kim L. Rice, Jonathan D. Licht
Abstract | Full text | PDF (Page 865)
Hypoglycemia, functional brain failure, and brain death
Philip E. Cryer
Abstract | Full text | PDF (Page 868)
Yin and yang interplay of IFN-γ in inflammation and autoimmune disease
Jingwu Zhang
Abstract | Full text | PDF (Page 871)
The renin-angiotensin system: it’s all in your head
Kelly K. Parsons, Thomas M. Coffman
Abstract | Full text


May 2007
Murine models of Omenn syndrome
Serre-Yu Wong, David B. Roth
Abstract | Full text | PDF (Page 1213)
Cutaneous mosaicism: right before our eyes
Jorge Frank, Rudolf Happle
Abstract | Full text | PDF (Page 1216)
Cellular and molecular basis of wound healing in diabetes
Harold Brem, Marjana Tomic-Canic
Abstract | Full text | PDF (Page 1219)
Geranylgeranyltransferase I as a target for anti-cancer drugs
Mark R. Philips, Adrienne D. Cox
Abstract | Full text | PDF (Page 1223)
Pharmacogenetics of metformin response: a step in the path toward personalized medicine
Marc L. Reitman, Eric E. Schadt
Abstract | Full text |


June 2007
Vascular biology and bone formation: hints from HIF
Dwight A. Towler
Abstract | Full text | PDF (Page 1477)
Sizing up sialic acid in glomerular disease
Susan E. Quaggin
Abstract | Full text | PDF (Page 1480)
A beneficial role for IL-1β in Alzheimer disease?
Cynthia A. Lemere
Abstract | Full text | PDF (Page 1483)
Unchecked thrombin is bad news for troubled arteries
Eric Camerer
Abstract | Full text |


July 2007
Lost in a dark wood
Laurence A Turka
Full text


August 2007
Regulation of erythrocyte lifespan: do reactive oxygen species set the clock?
Shilpa M. Hattangadi, Harvey F. Lodish
Abstract | Full text | PDF (Page 2075)
Prime suspect: the TCF7L2 gene and type 2 diabetes risk
Andrew T. Hattersley
Abstract | Full text | PDF (Page 2077)
Proteinuria: is it all in the foot?
Pierre Ronco
Abstract | Full text | PDF (Page 2079)
Retroviral integration and human gene therapy
Frederic D. Bushman
Abstract | Full text | PDF (Page 2083)
When EGF is offside, magnesium is wasted
Shmuel Muallem, Orson W. Moe
Abstract | Full text | PDF (Page 2086)
“AMPing up” our understanding of the hypothalamic control of energy balance
Kevin W. Williams, Roberto Coppari, Joel K. Elmquist
Abstract | Full text | PDF (Page 2089)
New TB vaccines: is there a requirement for CD8+ T cells?
W. Henry Boom
Abstract | Full text


September 2007
Low-molecular-weight S-nitrosothiols and blood vessel injury
Philip A. Marsden
Abstract | Full text | PDF (Page 2377)
β Cell transplantation and immunosuppression: can’t live with it, can’t live without it
Klaus H. Kaestner
Abstract | Full text | PDF (Page 2380)
Deepening our understanding of immune sentinels in the skin
Frank O. Nestle, Brian J. Nickoloff
Abstract | Full text | PDF (Page 2382)
Taking aim at translation for tumor therapy
Bryan C. Barnhart, M. Celeste Simon
Abstract | Full text | PDF (Page 2385)
Two tales concerning skeletal muscle
David J. Glass
Abstract | Full text | PDF | Correction (Page 2388)
Rheostat regulation of integrin-mediated leukocyte adhesion
Ivor S. Douglas, Themistocles Dassopoulos
Abstract | Full text | PDF (Page 2391)
Alternative signaling: cardiomyocyte β1-adrenergic receptors signal through EGFRs
Stefan Engelhardt
Abstract | Full text |


October 2007
Navigating through the gray (and CMYK) areas of figure manipulation: rules at the JCI
Ushma Neill, Laurence A. Turka
Abstract | Full text |


November 2007
A method to our madness
Laurence A. Turka
Abstract | Full text


December 2007
B cell depletion: a novel therapy for autoimmune diabetes?
Hélène Bour-Jordan, Jeffrey A. Bluestone
Abstract | Full text | PDF (Page 3642)
Every allograft needs a silver lining
Alan G. Contreras, David M. Briscoe
Abstract | Full text | PDF (Page 3645)
Staying awake puts pressure on brain arousal systems
Giulio Tononi, Chiara Cirelli
Abstract | Full text | PDF (Page 3648)
Structural reengineering of imatinib to decrease cardiac risk in cancer therapy
George D. Demetri
Abstract | Full text | PDF (Page 3650)
The weight of cell identity
David T. Scadden
Abstract | Full text | PDF (Page 3653)
OX40-OX40L interactions: a promising therapeutic target for allergic diseases?
Yui-Hsi Wang, Yong-Jun Liu
Abstract | Full text | PDF (Page 3655)
Targeting mutant p53 shows promise for sunscreens and skin cancer
Wafik S. El-Deiry
Abstract | Full text | PDF (Page 3658)
IL-6 involvement in epithelial cancers
Zachary T. Schafer, Joan S. Brugge
Abstract | Full text