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Articles

Journal of Clinical Investigation - Commentaries 2004

ISSUE PERSPECTIVE/COMMENTARY
1 December 2004 Vol.141;11
(1)PPARs in atherosclerosis: the clot thickens
(2)Fusion of bone marrow-derived stem cells with striated muscle may not be sufficient to activate muscle genes
(3)Marfan syndrome and mitral valve prolapse
(4)Metabolic fuel selection: the importance of being flexible
15 November 2004 Vol.141;10
(1)RIP-ed and ready to dance:new mechanisms for polycystin-1 signaling
(2)Piecing together the puzzle of cutaneous mosaicism
(3)The multiple causes of human SCID
(4)What determines glomerular capillary permeability?
(5)Genes and pathophysiology of type 2 diabetes:more than just the Randle cycle all over again
1 November 2004 Vol.141;9
(1)Inflammatory bowel disease reveals the kinase activity of KSR1
(2)p16 and ARF: activation of teenage proteins in old age
(3)Developing DNA vaccines that call to dendritic cells
(4)Do DNA sequence variants on ABCA1 contribute to HDL cholesterol levels in the general population?
15 October 2004 Vol.141;8
(1)Reflecting on 80 years of excellence
1 October 2004 Vol.141;7
(1)Vasohibin:feedback on a new inhibitor of angiogenesis
(2)IRS2 take centre stage in the development of type 2 diabetes
(3)Lenti in red: progress in gene therapy for human hemoglobinopathies
(4)Gene therapy for type 1 diabetes:a novel approach for targeted treatment of autoimmunity
(5)Judging a virus by its cover
15 September 2004 Vol.141;6
(1)Bone marrow-derived stem cells preserve cone vision in retinitis pigmentosa
(2)Prostanoids and blood pressure:which way is up?
(3)Complements of the bone
(4)The link between IFN- and allograft arteriopathy:is the answer NO?
1 September 2004 Vol.141;5
Commentaries
(1)
Adenosine and ATP: traffic regulators in the kidney
(2)Why does diabetes increase atherosclerosis?I don't know!
(3)Anti-C1q autoantibodies amplify pathogenic complement activation in systemic lupus erythematosus
(4)Stat3 is required for the development of skin cancer
16 August 2004 Vol.141;4
Commentaries
(1)
RANKing c-Jun in osteolclast development
(2)AMP-activated protein kinase:the guardian of cardiac energy status
(3)Immune recognition of self in immunity against cancer
(4)The T-cell cometh:interplay between adaptive immunity and cytokine networks in rheumatoid arthritis
1 August 2004 Vol.141;3
Commentaries
(1)
Umbilical cord blood cells and brain stroke injury: brining in fresh blood to address an old problem
(2)Unlocking the secrets of pancreatic ß-cell: man and mouse provide the key
(3)IL-5 links adaptive and natural immunity in reducing atherosclerotic disease
(4)Pulmonary fibrosis: thinking outside of the lung
15 July 2004 Vol.141;2
Commentaries
(1)
Determination of the molecular basis for Marfan syndrome:a growth industry
(2)Unbuckling lipodystrophy from insulin resistance and hypertension
(3)Innate immunity dictates cytokine polarization relevant to the development of pulmonary fibrosis
(4)Adaptive cellular immunity in aortic aneurysms:cause,consequence,or context?
1 July 2004 Vol.141;1
Commentaries
(1)
A non-inflammatory pathway for pregnancy loss:innate immune activation?
(2)Lonely in Paris: when one gene copy isn't enough
(3)Coagulation-dependent mechanisms and asthma
(4)Atopic mechanisms in Alzheimer neurofibrilliary degeneration: cause of effect?
15 June 2004 Vol.140;12
Commentaries
(1)
Cleft palate:players,pathways,and pursuits
(2)Poliovirus proves IRES-istible in vivo
(3)Is transplantation tolerable?
1 June 2004 Vol.140;11
Commentaries
(1)
Inhibit GSK-3ß or there heartbreak dead ahead
(2)A fork in the road of cell differentiation in the kidney tubule
(3)The case of visceral fat:argument for the defense
(4)Getting stents to go with the flow
15 May 2004 Vol.140;10
Commentaries
(1)
Anti-ß1 receptor antibodies and heart failure:causation,jsu not correlation
(2)Dissecting the functional role of different isoforms of the L-type Ca2+ channel
(3)Amyloid at the cutting edge:activation of alfa-secretase prevents amyloidogenesis in an Alzheimer Disease mouse model
(4)Sepsis:avoiding its deadly toll
1 May 2004 Vol.140;9
Commentaries
(1)
Lost in transdifferentiation
(2)Anemia of inflammation:the cytokine-hepcidin link
(3)Hold the antioxidants and improve plasma lipids
(4)Dysbindin-1 and schizophernia:from genetics to neuropathology
15 April 2004 Vol.140;8
Commentaries
(1)
Blood to brain to the rescue
(2)Undermining the endothelium by ablation of MAPK-MEF2 signaling
(3)Insig:a significant integrator of nutrient and hormonal signals
(4)Experimental autoimmune hearing loss
15 March 2004 Vol.140;6
Commentaries
(1)
Fat's loss is bone's gain
(2)Predicting the clinical course of prostate cancer
(3)The immune response to AIDS virus infection:good,bad,or both?
(4)Sculpting organ innervation
1 March 2004 Vol.140;5
Commentaries
(1)
CD1a and langerin:acting as more than Langerhans cell markers
(2)Viral immunosuppression:disabling the guards
(3)The anatomy of an arrhythmia
(4)Immune system versus tumor:shifting the balance in favor of DC's and effective immunity
15 February 2004 Vol.140;4
Commentaries
(1)
Into the depths of ataxia
(2)The eosinophil enigma
(3)HDL action on the vascular wall:is the answer NO?
(4)Fighting cancer by disrupting C-terminal methylation of signaling ptoteins (to be linked)
1 February 2004 Vol.140;3
Commentaries
(1)
Achieving antigen-specific immune regulation
(2)How do mutations in lamins A and C cause disease?
(3)Nitrate tolerance,oxidative stress,and mitochondrial function:another worrisome chapter on the effects of organic nitrates
(4)Tandem mass spectrometry in discovery of disorders of the metabolome
15 January 2004 
Vol.140;2
Commentaries
(1)
The bone marrow leaves its scar:new concepts in pulmonary fibrosis
(2)Bateman domains and adenosine derivatives form a binding contract
(3)Synapses and Sisyphus:life without paraplegin
1 January 2004
Vol.140;1
Commentaries
(1)
Haldane,hot dogs,halitosis, and hypoxic vasodilation:the emerging biology of the nitrite anion
(2)New viruses shake old paradigms
(3)East meets West:an herbal tea finds a receptor
(4)The relative roles of growth hormone and IGF-1 in controlling insulin sensitivity